Published Papers & Posters using the TA.XT2 & TA.XTPlus Texture Analyzers for Pharmaceutical Applications & Research

The following list contains abstracts of papers that have stated the use of the Stable Micro Systems Texture Analysers within the pharmaceutical sector. Each list item starts with the name of the author(s). The papers are NOT the property of Stable Micro Systems so we can not therefore supply copies due to copyright laws, but if you have trouble finding them then please contact us (app.support@stablemicrosystems.com) and we will do our best to put you in touch with the author.

Last updated 2nd May 2002

Alginate Raft Systems
JOHNSON, F. A., CRAIG, D. Q. M., MERCER, A. D. & CHAUHAN, S. (1997). The effects of alginate molecular structure and formulation variables on the physical characteristics of alginate raft systems. International Journal of Pharmaceutics, 159, 35-42.

Bacterial Cellulose
CHUNG, Y. & SHYU, Y. (1999). The effects of pH, salt, heating and freezing on the physical properties of bacterial cellulose-nata. International Journal of Food Science and Technology, 34 (1), 23-26.

Bioadhesive Films
MOSS, G. P., WOOLFSON, A. D. & McCAFFERTY, D. F. (1999). Mechanical characterisation of Tetracaine-containing bioadhesive films for percutaneous local anaesthesia. Paper presented at the 18th Pharmaceutical Technology Conference, Utrecht, Holland, April 1999, 44-58.

Biogels
ANDREWS, G., JONES, D. & WOOLFSON, D. (2001). Characterisation of binary drug delivery platforms. Paper presented at 28th International Symposium on Controlled Release of Bioactive Materials, 23-27 June 2001, San Diego, USA.

Blood Plasma Gels
PARES, D., SAGUER, E., SAURINA, J., SUNOL, J. J. & CARRETERO, C. (1998). Functional properties of heat induced gels from liquid and spray-dried porcine blood plasma as influenced by pH. Journal of Food Science, 63 (6), 958-961.

Bones
RANHOTRA, G. S., GELROTH, J. A. & LEINEN, S. D. (1999). Increase in bone calcification in young rats fed breads highly fortified with calcium. Cereal Chemistry, 76 (3), 325-327.

STYLIANOPOULOUS, C., SALDIVAR, S. O. S. & MACKINNEY, G. A. (2002). Effects of fortification and enrichment of maize tortillas on growth and brain development of rat throughout two generations. Cereal Chemistry, 79 (1), 85-91.

Bone Substitute
IOOSS, P., LE RAY, A.-M., GRIMANDI, G., DACULSI, G. & MERLE, C. (2001). A new injectable bone substitute combining poly (E-caprolactone) microparticles with biphasic calcium phosphate granules. Biomaterials, 22, 2785-2794.

WEISS, P., GAUTHIER, O., BOULER, J.-M., GRIMANDI, G. & DACULSI, G. (1999). Injectable bone substitute using a hydrophilic polymer. Bone, 25 (2), 67S-70S.

Carbopol Organogels
MULDOON, B., JONES, D., WOOLFSON, D. & SANDERSON, D. (2001). Controlled release of Tetracycline from Carbopol organogels. Paper presented at 28th International Symposium on Controlled Release of Bioactive Materials, 23-27 June 2001, San Diego, USA.

Cellulose Films
FROHOFF-HULSMANN, M. A., LIPPOLD, B. C., MCGINITY, J. W. (1999). Aqueous ethyl cellulose dispersion containing plasticizers of different water solubility and hydroxypropyl methyl -cellulose as coating material for diffusion pellets II: properties of sprayed films. European Journal of Pharmaceutics and Biopharmaceutics, 48, 67-75.

Celluloseacetate Films
THO, I., SCHULTZ, P., WAALER, T. & KLEINEBUDDE, P. (1999). Mechanical properties of dry and wet free polymer films. Proceedings of the International Symposium of Controlled Release Bioactive Materials, 26, 1999.

Creams
JONES, D. S. & WOOLFSON, A. D. (1997). Measuring sensory properties of semi-solid products using texture profile analysis. Pharmaceutical Manufacturing Review, 9 (1).

TAMBURIC, S., CRAIG, D. Q. M., VULETA, G. & MILIC, J. (1996). An investigation into the use of thermorheology and texture analysis in the evaluation of W/O creams stabilised with a silicone emulsifier. Pharmaceutical Development and Technology, 1 (3), 299-306.

Faeces
SMIDT, C. R. (1994). Effects of hydrolyzed and intact psyllium and other dietary fibers on GI-function in cecectomized rats fed liquid diets. Poster presented at 18th Clinical Congress, San Antonio, February, 1994.

Gel Capsules
PILLAY, V. & FASSIHI, R. (1999). A new method for dissolution studies of lipid-filled capsules employing Nifedipine as a model drug. Pharmaceutical Research, 16 (2), 334-338.

Gel Pellets
PILLAY, V. & FASSIHI, R. (1999). In vitro release modulation from crosslinked pellets for site-specific drug delivery to the gastrointestinal tract: I - Physicochemical characterisation of calcium-alginate, calcium-pectinate and calcium-alginate-pectinate pellets. Journal of Controlled Release, 59, 243-256.

TALUKDER, R. & FASSIHI, R. (1999). Determination of dynamics of hydration by tracking phase transitions within a swelling matrix. Paper presented at AAPS Conference, New Orleans, 1999.

Hair
BARNES, H. A. & ROBERTS, G. P. (2000). The non-linear viscoelastic behaviour of human hair at moderate extensions. International Journal of Cosmetic Science, 22, 259-264.

JACHOWICZ, J. & MCMULLEN, R. (2000). Mechanical analysis of hair fiber assemblies by static and relaxation measurements. Paper presented at the XX1st IFSCC Congress, Berlin, Germany.

WALLS, W. & KRUMMEL, H. K. (1997). Styleze CC-10: Climate control from a styling polymer. Cosmetic and Toiletries Manufacture Worldwide, 219-223.

Hair Conditioners
JACHOWICZ, J. & YAO, K. (1996). The analysis of conditioners and fixative on caucasian, negroid, and oriental hair. 19th IFSCC International Congress, Sydney, Australia, October, 1996.

Hair Gel
JACHOWICZ, J. & YAO, K. (1997). Characterisation of cosmetic products by texture analysis. International conference of IFSCC and the 9th Hungarian Congress on Cosmetic and Household Chemicals.

Hair Fixative/Spray
JACHOWICZ, J. & YAO, K. (1996). Structure-property relationships for hair fixatives. 10th International Hair Science Symposium, Rostock, September, 1996.

JACHOWICZ, J. & YAO, K. (1996). Dynamic hairspray analysis. I. Instrumentation and preliminary results. J. Soc. Cosmet. Chem., 47, 73-84.

Hair Treatment Clay
JACHOWICZ, J. & YAO, K. (1997). Characterisation of cosmetic products by texture analysis. International conference of IFSCC and the 9th Hungarian Congress on Cosmetic and Household Chemicals.

Hot Melt Extruded Films
REPKA, M. A., PRODDUTURI, S. & STODGHILL, S. P. (2001). Bioadhesive and chemical properties of hydroxypropyl cellulose hot-melt extruded films containing Nystatin and Clotrimazole. Poster presented at AAPS Annual Meeting, Denver, Colorado, USA.

Hydro Gels
McCOY, C., GORMAN, S., JONES, D., McLAUGHLIN, D. & ROONEY, C. (2001). Characterisation of partially-biodegradable semi-interpenetrating polymer networks. Paper presented at 28th International Symposium on Controlled Release of Bioactive Materials, 23-27 June 2001, San Diego, USA.

SKULASON, S. KRISTMUNDSDOTTIR, T. & HOLBROOK, W. P. (2000). A technique for evaluating the adhesion of hydrogel compositions. Proceedings of the International Symposium of Controlled Release Bioactive Materials, Paris, 11-13 July, 2000.

Hydroxyethylcellulose Gels
CAMPBELL, K., MALCOLM, R. K., RUSSELL, J. A. & WOOLFSON, A. D. (1999). Rheological behaviour of pharmaceutical gels, suspensions and eutectic emulsions of Ibuprofen and Methyl Nicotinate. Paper presented at the 18th Pharmaceutical Technology Conference, Utrecht, Holland, April 1999, 201-213.

Lip Balm

TONGAREE, S., MOREFIELD, E. & PARTRIDGE, N. (2000). Instrumental evaluation of sensory attributes of lip balm formulations. Poster presented at AAPS Annual Meeting, Oct 29-Nov 2, 2000, Indianapolis, USA.

Lipstick
SMEWING, J. (1998). Analysing the textural properties of cosmetics. Cosmetics and Toiletries Manufacture Worldwide, 249-253.

Lyophilisates
THAPA, P., STEVENS, H. N. E. & BAILLIE, A. J. (1999). Lyophilised dosage form for the nasal delivery of drugs. Proceedings of the International Symposium of Controlled Release Bioactive Materials, 26, 1999.

Methyl Nicotinate Gels
CAMPBELL, K., MALCOLM, R. K., RUSSELL, J. A. & WOOLFSON, A. D. (1999). Rheological behaviour of pharmaceutical gels, suspensions and eutectic emulsions of Ibuprofen and Methyl Nicotinate. Paper presented at the 18th Pharmaceutical Technology Conference, Utrecht, Holland, April 1999, 201-213.

Oral Mucosal Patches
REPKA, M. A., MUNJAL, M., GUTTA, K. & STODGHILL, S. (2001). Physical and chemical properties of transmucosal hydroxypropyl cellulose and hydroxypropyl methylcellulose films containing Lidocaine. Poster presented at AAPS Annual Meeting, Denver, Colorado, USA.

Polysaccharide Gels
JONES, D. S., WOOLFSON, A. D. & DJOKIC, J. (1996). Texture profile analysis of bioadhesive polymeric semisolids: Mechanical characterization and investigation of interactions between formulation components. Journal of Applied Polymer Science, 61, 2229-2234.

JONES, D. S., WOOLFSON, A. D., & BROWN, A. F. (1997). Textural, viscoelastic and mucoadhesive properties of pharmaceutical gels composed of cellulose polymers. International Journal of Pharmaceutics, 151, 223-233.

JONES, D. S., WOOLFSON, A. D., BROWN, A. F. & O'NEILL, M. J. (1997). Mucoadhesive, syringeable drug delivery systems for controlled application of metronidazole to the periodontal pocket: In vitro release kinetics, syringeability, mechanical and mucoadhesive properties. Journal of Controlled Release, 49, 71-79.

McTAGGART, L. E. & HALBERT, G. W. (1993). Assessment of Polysaccharide Gels as Drug Delivery Vehicles. International Journal of Pharmaceutics, 100, 199-206.

NIELSEN, L. S., SCHUBERT, L. & HANSEN, J. (1998). Bioadhesive drug delivery systems I. Characterisation of mucoadhesive properties of systems based on glyceryl mono-oleate and glyceryl monolinoleate. European Journal of Pharmaceutical Sciences, 6, 231-239.

TAMBURIC, S. & CRAIG, D. Q. M. (1997). A comparison of different in vitro methods for measuring mucoadhesive performance. European Journal of Pharmaceutics and Biopharmaceutics, 44, 159-167.

TOBYN, M. J., STANIFORTH, J. N., JORGENSEN, E. & BHAGWAT, D. (1997). Use of gel strength analysis to characterise a polysaccharide controlled release matrix. Controlled Release of Bioactive Materials Conference Paper, 1997.

Polymer Gels
HAGERSTROM, H & EDSMAN, K. (2000). A new detachment force method for measuring mucoadhesion of gels intended for nasal administration - comparison with a rheological method. Proceedings of the International Symposium of Controlled Release Bioactive Materials, Paris, 11-13 July, 2000.

Poly(Methyl Vinyl Ether-Maleic Anhydride) gels
LAWLOR, M. S., JONES, D. S. & WOOLFSON, A. D. (1999). Analysis of the mechanical and rheological properties of Tetracycline-containing gels composed of Poly(Methyl Vinyl Ether-Maleic Anhydride) and Polyvinylpyrrolidone. Paper presented at the 18th Pharmaceutical Technology Conference, Utrecht, Holland, April 1999, 306-309.

LAWLOR, M. S., JONES, D. S. & WOOLFSON, A. D. (1999). Rheological and mechanical characterisation of Tetracycline-containing gels designed for the treatment of periodontal diseases. Proceedings of the International Symposium of Controlled Release Bioactive Materials, 26, 1999.

Pressed Powders
SMEWING, J. (1998). Analysing the textural properties of cosmetics. Cosmetics and Toiletries Manufacture Worldwide, 249-253.

Salivary Replacement Gel
KELLY, H. M., PURCELL, C. H. & DEASY, P. B. (2000). Development of a salivary replacement gel for the symptomatic treatment of xerostomia. Proceedings of the International Symposium of Controlled Release Bioactive Materials, Paris, 11-13 July, 2000.

Shampoo

JACHOWICZ, J. & YAO, K. (1997). Characterisation of cosmetic products by texture analysis. International conference of IFSCC and the 9th Hungarian Congress on Cosmetic and Household Chemicals.

Silicone Intravaginal Rings
GALLAGHER, R. J., MALCOLM, R. K., RUSSELL, J. A. & WOOLFSON, A. D. (1999). Determination of tensile and compressional properties of silicone intravaginal rings using a modified texture analyser. Paper presented at the 18th Pharmaceutical Technology Conference, Utrecht, Holland, April 1999, 288-297.

Skin Patches
SHIN, Y. H., LEE, Y. D. & KIM, J. J. (2001). Preparation and evaluation of a Ketorolac transdermal drug delivery system. Paper presented at 28th International Symposium on Controlled Release of Bioactive Materials, 23-27 June 2001, San Diego, USA.

WOOLFSON, A. D., McCAFFERTY, D. F. & MOSS, G. P. (1998). Development and characterisation of a moisture-activated bioadhesive drug delivery system for percutaneous local anaesthesia. International Journal of Pharmaceutics, In press.

Skin Wounds
BAIE, S. H. & SHEIKH, K. A. (1999). Effect of palm oil based creams containing Channa Striatus (Snake head fish) as an active ingredient on tensile strength of healing wounds in rats. Paper presented at: 18th Pharmaceutical Technology Conference, Utrecht, April, 1999.

Tablets
CONTE, U., MAGGI, L., TORRE, M. L., GIUNCHEDI, P. & LA MANNA, A. (1993). Press-coated tablets for time-programmed release of drugs. Biomaterials, 14 (13), 1017-1023.

DOR, J. M., CHAU, A., PREVYSH-ROGERS, V., CHU, J. & FIX, J. A. (2000). A new in-vitro method vs the standard USP method to measure the disintegration time of fast-disintegration tablets. Proceedings of the International Symposium of Controlled Release Bioactive Materials, Paris, 11-13 July, 2000.

DOR, P, J. M., FIX, J. A. & JOHNSON, M. I. (1999). A new in-vitro method to measure the disintegration time of a fast-disintegration tablet. Proceedings of the International Symposium of Controlled Release Bioactive Materials, 26, 1999.

MILLS, S., TOBYN, M. J. & STANIFORTH, J. N. (2001). Metered dose dermal drug delivery: Pandermal tablets. Poster presented at AAPS Annual Meeting, Denver, Colorado, USA.

PILLAY, V. & FASSIHI, R. (1999). Electrolyte-induced compositional heterogeneity: A novel approach for rate-controlled oral drug delivery. Journal of Pharmaceutical Sciences, 88 (11), 1140-1148.

PILLAY, V. & FASSIHI, R. (2000). In situ electrolyte interactions in a disk-compressed configuration system for up-curving and constant drug delivery. Journal of Controlled Release, 67, 55-65.

PILLAY, V., & FASSIHI, R. (2000). A novel approach for constant rate delivery of highly soluble bioactives from a simple monolithic system. Journal of Controlled Release, 67, 67-78.

TOBYN, M., JOHNSON, J. R. & GIBSON, S. (1994). Use of a TA.XT2 Texture Analyser in Mucoadhesive Research. International Labmate, Vol. XVII, Issue VI.

TOBYN, M. J., JOHNSON, J. R. & DETTMAR, P. W. (1995). Factors affecting in vitro gastric mucoadhesion I. Test conditions and instrumental parameters. European Journal of Pharmaceutics and Biopharmaceutics, 41 (4), 235-241.

TOBYN, M. J., JOHNSON, J. R. & DETTMAR, P. W. (1996). Factors affecting in vitro gastric mucoadhesion II. Physical properties of polymers. European Journal of Pharmaceutics and Biopharmaceutics, 42 (1), 56-61.

TOBYN, M. J., JOHNSON, J. R. & DETTMAR, P. W. (1997). Factors affecting in vitro gastric mucoadhesion IV. Influence of tablet excipients, surfactants and salts on the observed mucoadhesion of polymers. European Journal of Pharmaceutics and Biopharmaceutics, 43, 65-71.

YANG, L., JOHNSON, B. & FASSIHI, R. (1998). Determination of continuous changes in the gel layer thickness of poly(ethylene oxide) and HPMC tablets undergoing hydration: a texture analysis study. Pharmaceutical Research, 15 (12), 1902-1906.

ZULEGER, S., RASSIHI, R. & LIPPOLD, B. C. (2000). Texture analysis and photomicroscopy to investigate the swelling of controlled release cellulose ether tablets. Paper presented at APV Congress, Berlin, April 2000.

Vaseline
CORDES, D., KLEINEBUDDE, P. & MULLER, B. W. (1994). Determination of the Consistency of Semisolid Preparations using the Texture Analyser. Chair of Pharmaceutical Technology of the Christian Albrecht University, Kiel. Pharmazie 49 No. 2/3.

Wax
SHELLHAMMER, T. H., RUMSEY, T. R. & KROCHTA, J. M. (1997). Viscoelastic properties of edible lipids. Journal of Food Engineering, 33 (3), 305-320.

TONGAREE, S. & NOWACZYK, F. (2001). Response surface analysis for waxes in semi-solid products. Poster presented at AAPS Annual Meeting, Denver, Colorado, USA.